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Sangamo BioSciences Changes Name To Sangamo Therapeutics, Underscoring Focus On Clinical Development Of Genomic Therapies;


Clear procedure with new administration, organizational structure and clinical abilities will drive Sangamo’s industry-driving logical stage into human reviews

2017 concentration is Phase 1/2 studies for four lead programs, incorporating first ever in vivo genome altering clinical trials, with potential for information in late 2017/mid 2018

News: Sangamo Biosciences, Inc. (NASDAQ:SGMO) belongs to Healthcare sector and Biotechnology  industry. Sangamo Therapeutics, Inc. (NASDAQ: SGMO), the pioneer in restorative genome altering, declares that it has changed its corporate name, from “Sangamo BioSciences, Inc.” to “Sangamo Therapeutics, Inc.” Sangamo normal stock will keep on trading on the NASDAQ Global Select Market under the present ticker image: “SGMO.” The new corporate name underscores Sangamo’s attention on clinical improvement of genomic treatments utilizing the Company’s business driving stage advancements crosswise over genome altering, quality treatment, quality direction and cell treatment.

“Our new name, Sangamo Therapeutics, mirrors our dedication to propel our weighty science into the center for the improvement of transformative treatments for genuine, hereditarily tractable ailments,” said Sandy Macrae, M.B., Ch.B., Ph.D., Sangamo’s recently designated CEO. “Our researchers are pioneers in their fields, and in the course of the most recent two decades, they have built up the most exceptional, adaptable and exact devices accessible for genomic treatments. With new initiative, a smoothed authoritative structure, redesignd administration procedures and clear course from our board, Sangamo now has the concentration and capacities in clinical science and item improvement to propel this intense logical stage into clinical advancement.”

Macrae proceeded: “In 2017, we hope to enlist four clinical trials for our lead programs creating important new treatments for patients living with hemophilia An and B and lysosomal stockpiling issue MPS I and II. We will likewise work intimately with our teammate Bioverativ, the arranged turn off of Biogen’s hemophilia business, to propel improvement of our ZFN-intervened genome altering programs in two related hereditary issue, sickle cell ailment and beta thalassemia.”

Late achievements

Designated Sandy Macrae as president and CEO in June 2016

Designated other new senior pioneers including a main medicinal officer and head of clinical advancement, a central business officer, and also heads of specialized operations and assembling, item improvement, and interchanges. The Company additionally contracted new staff, extending abilities in business arranging, clinical improvement and restorative undertakings.

Gotten acknowledgment from the U.S. Sustenance and Drug Administration of the IND application for the AAV Factor 8 cDNA vector program (SB-525) in Hemophilia A

Set up new procedures for target assessment and program movement

Fabricated and discharged cGMP materials for all right now arranged clinical trials

Opened enlistment for SB-FIX Phase 1/2 clinical trial for treatment of hemophilia B

Needs and desires for 2017

Enlist Phase 1/2 clinical trials for Sangamo’s four lead programs with information expected possibly in late 2017 or mid 2018, once the Company has accumulated adequate amount of data from every review to comprehend clinical pertinence:

  • Hemophilia A: SB-525, AAV Factor 8 cDNA in vivo quality treatment
  • Hemophilia B: SB-FIX, in vivo genome altering
  • Mucopolysaccharidosis (MPS) I: SB-318, in vivo genome altering
  • MPS II: SB-913, in vivo genome altering
  • Broaden mechanical favorable circumstances of our zinc finger nuclease (ZFN) stage for genome altering
  • Propel novel conveyance techniques, including lipid nanoparticles, toward clinical advancement

Work intimately with teammate Bioverativ, the arranged turn off organization of Biogen’s hemophilia business, on the advancement of our ZFN-intervened genome altering programs for two uncommon blood issue, sickle cell malady and beta thalassemia

In accordance with beforehand expressed direction, Sangamo hopes to report a year-end 2016 adjust of money and money reciprocals of in any event $140 million, which will finance the Company’s operations past the consummation of each of the four Phase 1/2 clinical trials.

Summary: Sangamo Therapeutics, Inc. is centered around making an interpretation of earth shattering science into genomic treatments that change patients’ lives utilizing the organization’s business driving stage innovations in genome altering, quality treatment, quality direction and cell treatment. The Company’s exclusive zinc finger nuclease (ZFN) in vivo genome altering methodology is being assessed in Phase 1/2 clinical trials to treat hemophilia B and lysosomal stockpiling issue MPS I and MPS II. Sangamo is likewise leading a Phase 1/2 clinical trial to assess its AAV cDNA human Factor 8 quality treatment approach, SB-525, to treat hemophilia A. Sangamo has a key cooperation with Bioverativ, the arranged turn off organization of Biogen’s hemophilia business, for hemoglobinopathies, including sickle cell illness and beta-thalassemia, and with Shire plc to create therapeutics for Huntington’s sickness. Furthermore, Sangamo has Phase 1/2 and Phase 2 clinical projects in HIV/AIDS (SB-728). It has set up vital organizations with organizations in non-helpful uses of its innovation, including Dow AgroSciences and Sigma-Aldrich Corporation.